Tetrahedron Letters p. 1241 - 1244 (1989)
Update date:2022-07-30
Topics:
Cleve, A.
Bohlmann, F.
The first total synthesis of (+/-)-senoxepin 3 is described. 3 is prepared via an intramolecular <4+2> cycloaddition from a substituted decadienyne 7.The resulting hexalin 8 was converted to a lactone, which on epoxidation, NBS bromination and elimination with NaI afforded senoxepin.
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