1374961-66-6

Basic information

• Product Name: methyl 3-{N-(1-butyl)-2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]methoxy}benzamido}benzoate
• CAS NO: 1374961-66-6
• Molecular Weight: 629.968
• Mol File: 1374961-66-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-{N-(1-butyl)-2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]methoxy}benzamido}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-{N-(1-butyl)-2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]methoxy}benzamido}benzoate(1374961-66-6)
• EPA Substance Registry System: methyl 3-{N-(1-butyl)-2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]methoxy}benzamido}benzoate(1374961-66-6)

Safety Data

• Hazardous Substances Data: 1374961-66-6(Hazardous Substances Data)

Upstream product

• 278597-32-3 3-(2,6-dichlorophenyl)-4-(3'-chloro-4'-formylphenoxy)-methyl-5-isopropyl-isoxazole 
• 56962-11-9 2-chloro-4-hydroxybenzaldehyde 
• 933799-64-5 2-chloro-4-{[5-isopropyl-3-(2,6-dichlorophenyl)-isoxazol-4-yl]methoxy}benzoic acid 
• 898253-47-9 4-(bromomethyl)-3-(2,6-dichlorophenyl)-5-isopropyl-isoxazole 

Relevant articles and documents

Discovery and structural development of small molecules that enhance transport activity of bile salt export pump mutant associated with progressive familial intrahepatic cholestasis type 2

Progressive familial intrahepatic cholestasis type 2 (PFIC2) is caused by hereditary mutations of bile salt export pump (BSEP), such as E297G BSEP, which is a folding-defective mutant that is unable to traffic beyond the endoplasmic reticulum (ER). 4-Phen