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137506-94-6

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137506-94-6 Usage

Description

(5Z)-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one is a thiazolidine derivative with potent antioxidant properties. It features a thioxo-1,3-thiazolidin-4-one core and a 3,5-di-tert-butyl-4-hydroxybenzylidene moiety, which contribute to its ability to scavenge free radicals and protect against oxidative stress.

Uses

Used in Pharmaceutical Applications:
(5Z)-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one is used as a pharmaceutical agent for its potential role in the treatment or prevention of diseases related to oxidative damage. Its antioxidant activity may contribute to managing or mitigating the effects of neurodegenerative disorders and cardiovascular diseases.
Used in Cosmetic Applications:
In the cosmetic industry, (5Z)-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one is used as an ingredient in anti-aging or skin-care products. Its ability to neutralize free radicals can help protect the skin from oxidative stress, potentially reducing the visible signs of aging and promoting skin health.

Check Digit Verification of cas no

The CAS Registry Mumber 137506-94-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,5,0 and 6 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 137506-94:
(8*1)+(7*3)+(6*7)+(5*5)+(4*0)+(3*6)+(2*9)+(1*4)=136
136 % 10 = 6
So 137506-94-6 is a valid CAS Registry Number.

137506-94-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (5Z)-5-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

1.2 Other means of identification

Product number -
Other names HMS1477M05

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:137506-94-6 SDS

137506-94-6Relevant articles and documents

Synthesis and anti-inflammatory activity of (3,5-di-tert-butyl-4-hydroxybenzylidene) cyclanones and related compounds

Varache-Beranger,Nuhrich,Amiell,Dufour,Devaux

, p. 551 - 556 (1991)

Some (3,5-di-tert-butyl-4-hydroxybenzylidene) cyclanones were synthesized and evaluated for anti-inflammatory activity in carragenin-induced rat paw edema assay. These compounds are slightly less active than phenylbutazone. Their inhibitory effects in vit

Synthesis of enantioenriched 4-thiazolidinone (-)-LY213829 by chemoselective benzylamide cleavage in the presence of a C-S bond

Hansen, Marvin M.,Harkness, Allen R.,Khau, Vien V.,Martinelli, Michael J.,Deeter, Jack B.

, p. 2515 - 2518 (2007/10/03)

(R)-2-Methylbenzylamine has been used to covalently 'resolve' thiol acid 7 and assemble 4-thiazolidinone 8a in one step. Selective deprotection of the 2-methylbenzylamide using lithium in ammonia/THF has been achieved in the presence of a readily hydrogen

Pyridine derivatives, their production and use

-

, (2008/06/13)

There is disclosed a pharmaceutical composition for providing antiinflammatory, antipyretic, analgesic, antiallergic, immunosuppressing or immunomodulating activity which comprises a pyridine derivative of the formula (I): STR1 wherein R is an optionally substituted pyridine ring, X is a oxygen atom or --S(O)n--, wherein n is 0, 1 or 2, A is a bivalent C1-15 hydrocarbon residue whose branched moiety may have a substituent, Y is an oxygen or sulfur atom, R3 is a hydrogen atom or an optionally substituted hydrocarbon residue, R4 is an optionally substituted hydrocarbon residue or an optionally substituted monocyclic or bicyclic heterocyclic group, R3 and R4 may be joined together with the carbamoyl group or the thiocarbamoyl group to which they are attached to form an optionally substituted heterocyclic group, or R3 or R4 may be independently attached to A to form a ring, or a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier or diluent.

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