1375077-63-6Relevant articles and documents
Enzymatic synthesis of both enantiomeric forms of 3-allyloxy-propane-1,2- diol
Casati, Silvana,Santaniello, Enzo,Ciuffreda, Pierangela
, p. 395 - 400 (2012/07/14)
The stereoselective synthesis of (S)- and (R)-3-allyloxy-propane-1,2-diol has been accomplished in four steps from (RS)-3-allyloxy-propane-1,2-diol. Only one intermediate, namely 1-benzoyloxy-3-allyloxy-2-propanone has been prepared by a chemical reaction, that is, pyridinium chlorochromate oxidation of 1-benzoyloxy-3-allyloxypropan-2-ol. All of the remaining reactions (regioselective acylations, asymmetric bioreduction of prochiral ketones, and enzymatic alcoholysis) have been carried out in the presence of biocatalysts.