1375102-77-4

Basic information

• Product Name: 3',5-diallyl-4'-methoxy-[1,1'-biphenyl]-2-yl allylcarbamate
• CAS NO: 1375102-77-4
• Molecular Weight: 363.456
• Mol File: 1375102-77-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3',5-diallyl-4'-methoxy-[1,1'-biphenyl]-2-yl allylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5-diallyl-4'-methoxy-[1,1'-biphenyl]-2-yl allylcarbamate(1375102-77-4)
• EPA Substance Registry System: 3',5-diallyl-4'-methoxy-[1,1'-biphenyl]-2-yl allylcarbamate(1375102-77-4)

Safety Data

• Hazardous Substances Data: 1375102-77-4(Hazardous Substances Data)

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 68592-15-4 methylhonokiol 
• 107-11-9 1-amino-2-propene 

Relevant articles and documents

Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF1 production

A series of novel 4-O-methylhonokiol analogs were synthesized in light of revealing structure-activity relationship for inhibitory effect of COX-2 enzyme. The key strategy of the molecular design was oriented towards modification of the potential metabolic soft spots (e.g., phenol and olefin) or by altering the polar surface area via incorporating heterocycles such as isoxazole and triazole. Most of all exhibited the inhibitory effects on COX-2 and PGF 1 production but not macrophage NO production. Especially, aryl carbamates 10 and 11 exhibited more potent inhibitory activity against COX-2 and PGF1 production.