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1375108-41-0

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1375108-41-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1375108-41-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,5,1,0 and 8 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1375108-41:
(9*1)+(8*3)+(7*7)+(6*5)+(5*1)+(4*0)+(3*8)+(2*4)+(1*1)=150
150 % 10 = 0
So 1375108-41-0 is a valid CAS Registry Number.

1375108-41-0Relevant articles and documents

4,5,6,7-TETRAHYDRO-1 H-PYRAZOLO[4,3-C]PYRIDIN-3-AMINE COMPOUNDS AS CBP AND/OR EP300 INHIBITORS

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Page/Page column 219, (2016/06/14)

The present invention relates to compounds of formula (I) or formula (II): and to salts thereof, wherein R1-R4 of formula (I) and R1-R3 of formula (II) have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) of formula (II) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.

FATTY ACID SYNTHASE INHIBITORS

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Page/Page column 77, (2014/01/18)

This invention relates to novel spirocyclic piperidines according to Formula (I) which are inhibitors of fatty acid synthase (FAS), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

FATTY ACID SYNTHASE INHIBITORS

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Page/Page column 62, (2013/03/26)

This invention relates to spirocyclic piperidines according to Formula (I) and the use of spirocyclic piperidines for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of spirocyclic piperidines in the treatment of cancer.

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