59278-65-8

Basic information

• Product Name: 2-AMINO-4-BROMOBENZALDEHYDE
• Synonyms: 2-AMINO-4-BROMOBENZALDEHYDE;4-BroMo-2-aMinobenzaldehyde
• CAS NO: 59278-65-8
• Molecular Formula: C₇H₆BrNO
• Molecular Weight: 200.03
• Product Categories: Aromatic Aldehydes & Derivatives (substituted)
• Mol File: 59278-65-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: 85 °C
• Boiling Point: 317.1±32.0 °C(Predicted)
• Appearance: /
• Density: 1.672±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: -0.72±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4-BROMOBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-BROMOBENZALDEHYDE(59278-65-8)
• EPA Substance Registry System: 2-AMINO-4-BROMOBENZALDEHYDE(59278-65-8)

Safety Data

• Hazardous Substances Data: 59278-65-8(Hazardous Substances Data)

Usage

General Description

2-Amino-4-Bromobenzaldehyde is an organic compound that belongs to the class of organic compounds known as bromobenzenes. These are aromatic compounds containing one or more bromine atoms attached to a benzene. This chemical features an aldehyde functional group (-CHO), attached to a benzene ring, and a bromine atom and an amino group (-NH2) substituted onto the ring. It is primarily used in chemical synthesis applications, specifically in the synthesis of various pharmaceutical drugs and other organic compounds. It is typically handled and stored in a controlled environment due to its reactive nature. Its physical properties might include a high melting point and a strong, pungent smell, which are common amongst aldehyde compounds. Its molecular formula is C7H6BrNO. 2-Amino-4-Bromobenzaldehyde should be handled with care due to its potential hazards that can be harmful to skin, eyes, and if ingested or inhaled.

Upstream product

• 5551-12-2 4-bromo-2-nitrobenzaldehyde 
• 20776-50-5 2-amino-4-bromobenzoic acid 
• 946122-05-0 (2-amino-4-bromophenyl)methanol 
• 135484-83-2 2-amino-4-bromo-benzoic acid methyl ester 
• 20712-12-3 (2-amino-5-bromophenyl)methanol 
• 99474-21-2 (E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine 
• 60956-26-5 4-bromo-2-nitrotoluene 
• 22996-19-6 (4-bromo-2-nitrophenyl)methanol 
• 99277-71-1 4-bromo-2-nitrobenzoic acid 

Downstream Products

• 953039-65-1 7-bromo-quinazolin-2-ol 
• 332135-42-9 2-benzyl-7-bromo-3-methoxyquinoline 
• 332135-43-0 2-benzyl-7-pyrazyl-3-methoxyquinoline 
• 1296950-66-7 7-bromoquinolin-3-carboxamide 
• 1266322-58-0 7-bromoquinolin-3-amine 
• 883149-59-5 7-bromo-3-(2,5-dimethoxyphenyl)-1H-quinolin-2-one 
• 1228552-87-1 1-(7-bromoquinolin-3-yl)ethan-1-one 
• 1375108-40-9 7-bromo-3-quinolinecarbonitrile 
• 1057217-63-6 7-bromoquinoline-2-carboxylic acid 

Relevant articles and documents

Cationic Iridium-Catalyzed Asymmetric Decarbonylative Aryl Addition of Aromatic Aldehydes to Bicyclic Alkenes

We report an unprecedented catalytic protocol for the enantioselective decarbonylative transformation of aryl aldehydes. In this process, the decarbonylation of aldehydes catalyzed by chiral iridium complexes enabled the formation of asymmetric C?C bonds

PPTS-Catalyzed Bicyclization Reaction of 2-Isocyanobenzaldehydes with Various Amines: Synthesis of Diverse Fused Quinazolines

A PPTS (pyridinium p-toluenesulfonate)-catalyzed bicyclization reaction of 2-isocyanobenzaldehydes as 1,5-dielectrophiles with various amines has been developed. The reaction not only provides a simple and efficient strategy for the assembly of structurally diverse fused quinazoline derivatives from readily available substrates under metal-free and mild conditions in a single step with only water and hydrogen as the by-products, but also opens the way to the application of o-formyl arylisocyanides in the synthesis of nitrogen-containing heterocycles. (Figure presented.).

AMINOQUINOLINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF

The invention provides immunoconjugates of Formula (I) comprising an antibody linked by conjugation to one or more aminoquinoline derivatives. The invention also provides aminoquinoline derivative intermediate compositions of Formula (III) comprising a re