1375148-47-2Relevant academic research and scientific papers
1H-1,2,3-triazole-tethered uracil-ferrocene and uracil-ferrocenylchalcone conjugates: Synthesis and antitubercular evaluation
Singh, Amandeep,Biot, Christophe,Viljoen, Albertus,Dupont, Christian,Kremer, Laurent,Kumar, Kewal,Kumar, Vipan
, p. 856 - 861 (2017)
Copper-catalyzed azide-alkyne [3?+?2] cycloaddition has been utilized for preparing a series of 1H-1,2,3-triazoles with the purpose of probing structure–activity relationships among a uracil-ferrocene-triazole conjugate family. The antitubercular evaluati
Synthesis and: In vitro anti-proliferative evaluation of naphthalimide-chalcone/pyrazoline conjugates as potential SERMs with computational validation
Awolade, Paul,Kaur, Mandeep,Kumar, Vipan,Oluwakemi, Ebenezer,Pankaj,Saha, Sourav Taru,Shalini,Singh, Parvesh
, p. 15836 - 15845 (2020/05/13)
A series of naphthalimide-chalcone/pyrazoline conjugates was prepared and evaluated for their anti-breast cancer potential against estrogen responsive, i.e. MCF-7 (ER+), and triple-negative, i.e. MDA-MB-231 (ER-), cell lines. The structure-activity-relati
1 H -1,2,3-Triazole-tethered isatin-ferrocene and isatin-ferrocenylchalcone conjugates: Synthesis and in vitro antitubercular evaluation
Kumar, Kewal,Carrere-Kremer, Severine,Kremer, Laurent,Guerardel, Yann,Biot, Christophe,Kumar, Vipan
, p. 5713 - 5719 (2013/11/19)
A Cu-mediated azide-alkyne cycloaddition protocol has been employed for the synthesis of 16 different triazoles to probe the antitubercular structure-activity relationships within the isatin-ferrocene-triazole conjugate family. The antitubercular evaluati
Synthesis and in vitro anti-tubercular evaluation of 1,2,3-triazole tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone chimeric scaffolds
Kumar, Kewal,Singh, Pardeep,Kremer, Laurent,Guerardel, Yann,Biot, Christophe,Kumar, Vipan
, p. 5778 - 5781 (2012/06/04)
Twenty different triazoles were prepared to probe the anti-tubercular structure-activity relationships (SAR) within the β-lactam-ferrocene- triazole conjugate family. The compounds have been synthesized by copper-catalyzed "click chemistry". In vitro anti
