1375415-10-3

Upstream product

• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 536-74-3 phenylacetylene 
• 118887-70-0 2-azido-1-(4-fluoro-phenyl)-ethanone 
• 679842-59-2 1-allyl-4-phenyl-1H-1,2,3-triazole 

Relevant academic research and scientific papers

Catalytic asymmetric synthesis of β-triazolyl amino alcohols by asymmetric transfer hydrogenation of α-triazolyl amino alkanones

The synthesis of optically active β-triazolyl amino alcohols was carried out via ruthenium catalyzed asymmetric transfer hydrogenation of α-triazolyl amino alkanones. This reaction proceeds under mild reaction conditions with up to 99% yield and 99.9% ena

Enantioselective separation of (±)-β-hydroxy-1,2,3-triazoles by supercritical fluid chromatography and high-performance liquid chromatography

This paper reports the enantioseparation of β-hydroxy-1,2,3-triazole derivatives, which present a broad range of biological properties, by supercritical fluid chromatography (SFC) and high-performance liquid chromatography techniques (HPLC). Polysaccharid

Copper(II) bis-thiazole complex immobilized on silica nanoparticles: Preparation, characterization and its application as a highly efficient catalyst for click synthesis of 1,2,3-triazoles

In this work, the preparation of copper(II) complex of 3,5-bis(2-benzothiazolyl)pyridine, Cu(II)Br2-BTP, supported on nano silica functionalized with trimethoxysilylpropylchloride, Cu(II)Br2-BTP@TMSP-nSiO2, is reported. Th

Preparation method of triazole substituted acetophenone compound

The invention relates to a preparation method of a triazole substituted acetophenone compound. The preparation method comprises the following steps: a catalyst, a 1,4-disubstituted-1,2,3-triazole compound, an alpha-brominated acetophenone compound and alkali are successively added in a solvent, and react for 24 hours at the temperature of 80 to 140 DEG C, and a reaction solution is obtained after the reaction is complete; the reaction solution is subjected to the conventional extraction, drying, concentration and separation of column chromatography in sequence, and then the triazole substituted acetophenone compound is obtained. The preparation method of the triazole substituted acetophenone compound disclosed by the invention is simple to operate and high in product yield, can realize large-scale production, and has good application potential in medicines, pesticides, organic synthesis and materials, thereby having good industrial application prospects.

Polystyrene-supported ionic liquid copper complex: A reusable catalyst for one-pot three-component click reaction

Copper(II) complex of 1,2-bis(4-pyridylthio)ethane immobilized on polystyrene was a used as a highly stable, active, reusable and green catalyst for click synthesis of 1,2,3-triazoles via one-pot three-component reaction of organic halides, sodium azide a

Copper immobilized on Nanosilica Triazine Dendrimer (Cu(II)-TD@nSiO 2)-catalyzed regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles and bis- and tris-triazoles via a one-pot multicomponent click reaction

An efficient, atom-economical, and regioselective synthesis of a wide range of 1,4-disubstituted 1,2,3-triazoles in excellent yields has been achieved via a one-pot three-component reaction of alkynes and sodium azide with organic halides or α-bromo keton