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1375475-66-3

2-hydroxyl-3,9-diethoxy-10-methoxy-13-n-octylprotoberberine chloride is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 2-hydroxyl-3,9-diethoxy-10-methoxy-13-n-octylprotoberberine chloride

    Cas No: 1375475-66-3

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  • 1375475-66-3 Structure

  • Basic information

    1. Product Name: 2-hydroxyl-3,9-diethoxy-10-methoxy-13-n-octylprotoberberine chloride
    2. Synonyms: 2-hydroxyl-3,9-diethoxy-10-methoxy-13-n-octylprotoberberine chloride
    3. CAS NO:1375475-66-3
    4. Molecular Formula:
    5. Molecular Weight: 514.105
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1375475-66-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-hydroxyl-3,9-diethoxy-10-methoxy-13-n-octylprotoberberine chloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-hydroxyl-3,9-diethoxy-10-methoxy-13-n-octylprotoberberine chloride(1375475-66-3)
    11. EPA Substance Registry System: 2-hydroxyl-3,9-diethoxy-10-methoxy-13-n-octylprotoberberine chloride(1375475-66-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1375475-66-3(Hazardous Substances Data)

1375475-66-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1375475-66-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,5,4,7 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1375475-66:
(9*1)+(8*3)+(7*7)+(6*5)+(5*4)+(4*7)+(3*5)+(2*6)+(1*6)=193
193 % 10 = 3
So 1375475-66-3 is a valid CAS Registry Number.

1375475-66-3Upstream product

1375475-66-3Downstream Products

1375475-66-3Relevant articles and documents

Synthesis, structure-activity relationship and in vitro anti-mycobacterial evaluation of 13-n-octylberberine derivatives

Liu, Yan-Xin,Xiao, Chun-Ling,Wang, Yan-Xiang,Li, Ying-Hong,Yang, Yan-Hui,Li, Yang-Biao,Bi, Chong-Wen,Gao, Li-Mei,Jiang, Jian-Dong,Song, Dan-Qing

, p. 151 - 158 (2012)

Twenty-eight new 13-n-octylberberine derivatives were synthesized and evaluated for their activities against drug-susceptible Mycobacterium tuberculosis (M. tuberculosis) strain H37Rv. Among these compounds, compound 16e was the most effective anti-tubercular agent with a MIC value of 0.125 μg/mL. Importantly, compound 16e exhibited more potent effect against rifampicin (RIF)- and isoniazid (INH)-resistant M. tuberculosis strains than both RIF and INH, suggesting a new mechanism of action. Therefore, it has been selected as a drug candidate for further investigation, or as a chemical probe for identifying protein target and studying tuberculosis biology. We consider 13-n-octylberberine analogs to be a promising novel class of antituberculars against multi-drug-resistant (MDR) strains of M. tuberculosis.

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