137604-26-3

Upstream product

• 137604-22-9 (S)-4-azido-3-N,N-dibenzylaminobutanenitrile 
• 131270-10-5 (S)-3-N,N-dibenzylamino-4-mesyloxybutanenitrile 
• 137428-32-1 (2S)-2-[bis(phenylmethyl)amino]-1,4-butanediol 
• 159497-82-2 (S)-2-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>-1-butylamine 
• 137604-24-1 (S)-4-azido-3-N,N-dibenzylaminobutanoic acid 
• 159497-65-1 N,N-dibenzylasparaginic acid dibenzyl ester 
• 152299-02-0 (S)-1-<2-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>butyl>-N-phthalimide 
• 152298-97-0 (R)-2-<1-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>butyl> methanesulfonate 
• 152299-13-3 (2S)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-(dibenzylamino)butan-1-ol 
• 152298-92-5 (R)-N,N-dibenzyl-4-<(tert-butyldimethylsilyl)oxy>-2-chloro-1-butylamine 

Downstream Products

• 137604-28-5 (S)-3-N,N-dibenzylamino-4-N-pyrrolylbutanol 
• 159497-97-9 tert-butyl (S)-1-<1-<2-(N,N-dibenzylamino)-4-bromobutyl>>-3-hydroxypyrrole-2-carboxylate 
• 137604-30-9 (S)-6-N,N-dibenzylamino-5,6,7,8-tetrahydroindolizine 
• 159497-96-8 tert-butyl (S)-1-<1-<2-(N,N-dibenzylamino)-4-hydroxybutyl>>-3-hydroxypyrrole-2-carboxylate 

Relevant academic research and scientific papers

Enantiomerically pure amino alcohols and diamino alcohols from L-aspartic acid. Application to the synthesis of epi- and diepislaframine

Starting from natural aspartic acid (6) a practical method for the synthesis of enantiomerically pure 3-amino alcohols 8 including 3,4-diamino derivatives is described. After perbenzylation of 6 and reduction of both carboxylates, position 4 of the result

SYNTHESIS OF CHIRAL INDOLIZINES AS BICYCLIC ERGOLINE ANALOGUES

An efficient synthesis of the enantiomerically pure aminoindolizine (3) by a triflic anhydride assisted cyclization of the 1,3-amino alcohol (6) is reported. 6 can be readily derived from L-asparagine (4) via the O-activated β-homoserine equivalent (7).