137610-07-2

Upstream product

• 137694-02-1 (-)-(3R)-3-(tert-butyl)-2,3-dihydro-2-(1-oxoprop-2-enyl)-1,2-benzisothiazole 1,1-dioxide 
• 932-90-1 Benzaldoxime 
• 65818-60-2 3-(tert-butyl)-1,2-benzisothiazol-1,1-dioxide 
• 137695-25-1 1-((S)-3-tert-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzo[d]isothiazol-2-yl)-propenone 
• 81-07-2 saccharin 
• 137610-06-1 (S)-1-((S)-3-tert-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzo[d]isothiazole-2-sulfonylmethyl)-7,7-dimethyl-bicyclo[2.2.1]heptan-2-one 
• 137694-01-0 (S)-3-tert-butyl-2,3-dihydrobenzo[d]isothiazoline 1,1-dioxide 
• 131556-34-8 3-(tert-butyl)-2,3-dihydrobenzo[d]isothiazole-1,1-dioxide 
• 137610-06-1 (S)-1-((R)-3-tert-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzo[d]isothiazole-2-sulfonylmethyl)-7,7-dimethyl-bicyclo[2.2.1]heptan-2-one 
• 137694-00-9 (R)-3-tert-butyl-2,3-dihydrobenzo[d]isothiazoline 1,1-dioxide 

Downstream Products

• 124154-34-3 (S)-5-(Hydroxymethyl)-Δ²-isoxazoline 

Relevant academic research and scientific papers

Enantiomerically pure isoxazolines via addition of nitrile oxides to chiral N-acryloyl toluene-2,α-sultams

New saccharine-derived, crystalline acryloylsultams 12 undergo efficient 1,3-dipolar cycloadditions of nitrile oxides with ≥ 95:5 stereoface discrimination. Products 13 or 14 are purified by simple crystallization and cleaved with recovery of the chirophore to provide optically pure Δ2-isoxazolines 15.