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Product FOB Price Min.Order Supply Ability Supplier
High purity Saccharin 98% TOP1 supplier in China
Cas No: 81-07-2
No Data 100 Metric Ton 1-1000 Kilogram/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
High purity Various Specifications Saccharin CAS:81-07-2
Cas No: 81-07-2
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
Fresh In Stock:o-Benzoic sulfimide with BEST PRICE
Cas No: 81-07-2
USD $ 1.0-1.0 / Metric Ton 1 Metric Ton 1000 Metric Ton/Day Scale Chemical Corporation Contact Supplier
Insoluble Saccharin
Cas No: 81-07-2
USD $ 2.0-3.0 / Kilogram 1 Kilogram 50 Metric Ton/Day EAST CHEMSOURCES LIMITED Contact Supplier
High quality Saccharin supplier in China
Cas No: 81-07-2
No Data No Data No Data Simagchem Corporation Contact Supplier
Saccharin CAS: 81-07-2
Cas No: 81-07-2
USD $ 1.0-2.0 / Metric Ton 5 Metric Ton 1000 Metric Ton/Year Henan Sinotech Import&Export Corporation Contact Supplier
1981-7-2 C7H5NO3S Saccharin
Cas No: 81-07-2
No Data 5 Gram 1 Kilogram/Day HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
Saccharin CAS.81-07-2
Cas No: 81-07-2
No Data 1 Kilogram 1000 Metric Ton/Week Crovell Biotech (Hebei) Co., Ltd. Contact Supplier
TIANFU-CHEM - Saccharin
Cas No: 81-07-2
No Data 1 Kilogram 10 Metric Ton/Month Henan Tianfu Chemical Co., Ltd. Contact Supplier
Factory Supply 99% Food additives sweetener Saccharin Powder In bulk
Cas No: 81-07-2
No Data 25 Kilogram 1000 Metric Ton/Month Shaanxi Mingqi Chemical Co., Ltd Contact Supplier

81-07-2 Usage

General Description

White crystals. Odorless or faintly aromatic odor. Sweet taste.


ChEBI: A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.

Reactivity Profile

An amide. Acid to litmus. pH of 0.35% aqueous solution: 2.0. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).


Usually used in high performance liquid chromatographic method for the simultaneous separation and determination of acesulfame potassium, saccharine and aspartame;and also used in sweet preference test of rats.

Fire Hazard

Flash point data for Saccharin are not available; however, Saccharin is probably combustible.

Purification Methods

Purify saccharin by recrystallisation from Me2CO [solubility 7.14% at 0o, 14.4% at 50o], or aqueous isoPrOH to give a fluorescent solution. It sublimes in vacuo. It is an artificial sweetner and is 500 times sweeter than sucrose. [DeGarmo et al. J Am Pharm Assoc (Sci Ed) 41 17 1952, Beilstein 27 H 168, 870, 27 I 266, 27 II 214, 27 III/IV 2649.]


It is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing.

Chemical Properties

white crystalline solid


Saccharin is stable when heated and does not chemically react with other food ingredients, therefore, it stores well. When blended with other sweeteners, saccharin often compensates for each sweetener’s faults and weakness. Commonly, saccharin is used with aspartate in diet carbonated soft drinks.
Saccharin is insoluble in water in its acid form. Its majorly used form as an artificial sweetener is its sodium salt.

Safety and Health Effects

The utilization of saccharin in human food has raised numerous health and safety concerns. In the 1970s, saccharin was linked with the development of bladder in rodents in various laboratory studies on rats. Consequently, the United States Food and Drug Administration (FDA) pushed for its ban, sighting that it is carcinogenic to humans.
However, after strong objection from the public regarding the ban, American Congress intervened and allowed the compound to remain in the food supply as long as all the manufactures libel it with a warning when packaging.
Saccharin gas been classified to have no nutritional or food energy value, as such, it safe for patients with diabetes.

Air & Water Reactions

Slightly soluble in water.


Saccharin was discovered in 1879 by chemists Constantin Fahlberg and Ira Remsen as they were researching about the oxidation of o-toluenesulfonamide. While eating, Fahlberg noticed the presence of sweetness in his food due to his arms and hands that contained saccharin. As he checked his laboratory apparatus by taste tests, Fahlberg found out that the source of this sweetness was from saccharin. Saccharin is still made of toluenesulfonamide and from phthalic anhydride.

Brand name

Sweeta (Bristol-Myers Squibb).


Saccharin is an organic compound that is normally used as a non-nutritive sweetening agent. Also known as ortho-sulfobenzoic acid imide, saccharin occurs in the form of various salts, mainly calcium and sodium.

81-07-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Aldrich (109185)  Saccharin  ≥98% 81-07-2 109185-500G 893.88CNY Detail
Aldrich (109185)  Saccharin  ≥98% 81-07-2 109185-250G 603.72CNY Detail
Aldrich (240931)  Saccharin  ≥99% 81-07-2 240931-50G 939.51CNY Detail
Aldrich (240931)  Saccharin  ≥99% 81-07-2 240931-1G 363.87CNY Detail
Sigma-Aldrich (41131)  Mettler-Toledo Calibration substance ME 51143091, Saccharin  traceable to primary standards (LGC) 81-07-2 41131-5G 1,207.44CNY Detail
USP (1607007)  Saccharin  United States Pharmacopeia (USP) Reference Standard 81-07-2 1607007-200MG 4,662.45CNY Detail
Sigma-Aldrich (S0040000)  Saccharin  European Pharmacopoeia (EP) Reference Standard 81-07-2 S0040000 1,880.19CNY Detail
Sigma-Aldrich (PHR1341)    pharmaceutical secondary standard; traceable to USP and PhEur 81-07-2 PHR1341-1G 732.19CNY Detail
Alfa Aesar (B23938)  o-Benzoic sulfimide, 98+%    81-07-2 2500g 2685.0CNY Detail
Alfa Aesar (B23938)  o-Benzoic sulfimide, 98+%    81-07-2 500g 701.0CNY Detail
Alfa Aesar (B23938)  o-Benzoic sulfimide, 98+%    81-07-2 100g 217.0CNY Detail
TCI America (B0004)  o-Sulfobenzimide  >99.0%(HPLC)(T) 81-07-2 500g 535.00CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name saccharin

1.2 Other means of identification

Product number -
Other names 3-keto-2H,3H-1,2-benzisothiazole 1,1-dioxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food Additives: SWEETENER
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81-07-2 SDS

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