1376191-39-7

Basic information

• Product Name: (S)-ethyl 4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-(4-iodophenyl)-1H-pyrrole-2-carboxylate
• Synonyms: (S)-ethyl 4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-(4-iodophenyl)-1H-pyrrole-2-carboxylate
• CAS NO: 1376191-39-7
• Molecular Weight: 579.862
• Mol File: 1376191-39-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-ethyl 4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-(4-iodophenyl)-1H-pyrrole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-ethyl 4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-(4-iodophenyl)-1H-pyrrole-2-carboxylate(1376191-39-7)
• EPA Substance Registry System: (S)-ethyl 4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-(4-iodophenyl)-1H-pyrrole-2-carboxylate(1376191-39-7)

Safety Data

• Hazardous Substances Data: 1376191-39-7(Hazardous Substances Data)

Upstream product

• 140-53-4 p-chlorobenzyl cyanide 
• 15164-44-0 p-(iodophenyl)carboxaldehyde 
• 1376191-35-3 ethyl 4-(4-chlorophenyl)-3-(4-iodophenyl)-1H-pyrrole-2-carboxylate 
• 67987-67-1 (4S)-4-(2-iodoethyl)-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 1376191-48-8 (S)-4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-N-[3-(4-methylpiperazin-1-yl)propyl]-3-{4-[4-(4-nitrophenyl)piperazin-1-yl]phenyl}-1H-pyrrole-2-carboxamide 
• 1376190-36-1 4-(4-chlorophenyl)-1-[(S)-3,4-dihydroxybutyl]-3-(4-{4-[4-(4-{[(R)-4-(dimethylamino)-1-(phenylthio)but-2-yl]amino}-3-nitrophenylsulfonamido)phenyl]piperazin-1-yl}phenyl)-N-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrole-2-carboxamide 
• 1376191-43-3 (S)-ethyl 4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-{4-[4-(4-nitrophenyl)piperazin-1-yl]phenyl}-1H-pyrrole-2-carboxylate 

Relevant articles and documents

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Employing a structure-based strategy, we have designed a new class of potent small-molecule inhibitors of the anti-apoptotic proteins Bcl-2 and Bcl-xL. An initial lead compound with a new scaffold was designed based upon the crystal structure of Bcl-xL an