Cas 137643-15-3,2-(4-Bromo-2-fluoro-benzyl)-4-ethylcarbamoylmethyl-1,3-dioxo-1,2,3,4-tetrahydro-isoquinoline-4-carboxylic acid methyl ester

137643-15-3

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Basic information

Product Name: 2-(4-Bromo-2-fluoro-benzyl)-4-ethylcarbamoylmethyl-1,3-dioxo-1,2,3,4-tetrahydro-isoquinoline-4-carboxylic acid methyl ester
Synonyms:
CAS NO:137643-15-3
Molecular Formula:
Molecular Weight: 491.314
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2-(4-Bromo-2-fluoro-benzyl)-4-ethylcarbamoylmethyl-1,3-dioxo-1,2,3,4-tetrahydro-isoquinoline-4-carboxylic acid methyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 2-(4-Bromo-2-fluoro-benzyl)-4-ethylcarbamoylmethyl-1,3-dioxo-1,2,3,4-tetrahydro-isoquinoline-4-carboxylic acid methyl ester(137643-15-3)
EPA Substance Registry System: 2-(4-Bromo-2-fluoro-benzyl)-4-ethylcarbamoylmethyl-1,3-dioxo-1,2,3,4-tetrahydro-isoquinoline-4-carboxylic acid methyl ester(137643-15-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 137643-15-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 137643-15-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,6,4 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 137643-15:
(8*1)+(7*3)+(6*7)+(5*6)+(4*4)+(3*3)+(2*1)+(1*5)=133
133 % 10 = 3
So 137643-15-3 is a valid CAS Registry Number.

137643-15-3Upstream product

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137643-15-3Relevant academic research and scientific papers

N-substituted spirosuccinimide, spiropyridazine, spiroazetidine, and acetic acid aldose reductase inhibitors derived from isoquinoline-1,3- diones. 2

Malamas,Hohman

, p. 2059 - 2070 (2007/10/02)

The isoquinoline-1,3-dione framework featured in our clinical candidate (1) and its congener was used as the template in the design of several new series of aldose reductase inhibitors (ARIs). These series included N'- substituted spirosuccinimide, spirop

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