1376514-45-2

Upstream product

• 1376514-43-0 (S)-tert-butyl 1-(benzyloxy)hexan-3-ylcarbamate 
• 230637-46-4 (S)-tert-butyl (1-hydroxyhexan-3-yl)carbamate 
• 1376514-42-9 tert-butyl {3-[4-(chloromethyl)-3-methoxyphenoxy]propoxy}dimethylsilane 
• 1256497-70-7 2-amino-5-{4-[3-(tert-butyldimethylsilyloxy)propoxy]-2-methoxybenzyl}-6-methylpyrimidin-4-yl 2,4,6-trimethylbenzenesulfonate 
• 1376514-44-1 (S)-1-(benzyloxy)hexan-3-amine 
• 1256497-69-4 2-amino-5-{4-[3-(tert-butyldimethylsilyloxy)propoxy]-2-methoxybenzyl}-6-methylpyrimidin-4-ol 
• 1256497-68-3 methyl 2-{4-[3-(tert-butyldimethylsilyloxy)propoxy]-2-methoxybenzyl}-3-oxobutanoate 
• 1256497-66-1 {4-[3-(tert-butyldimethylsilyloxy)propoxy]-2-methoxyphenyl}methanol 
• 1256497-65-0 4-[3-(tert-butyldimethylsilyloxy)propoxy]-2-methoxybenzaldehyde 
• 64197-80-4 (S)-(+)-3-amino-1-hexanol 
• 18278-34-7 4-hydroxy-2-methoxybenzaldehyde 
• 89031-84-5 3-(tert-butyldimethylsilyloxy)propyl bromide 

Downstream Products

• 1376514-49-6 (3S)-3-[(2-amino-5-{4-[3-(dimethylamino)propoxy]-2-methoxybenzyl}-6-methylpyrimidin-4-yl)amino]hexan-1-ol 
• 1378275-52-5 (S)-3-(2-amino-5-{4-[3-(2-hydroxyethylamino)propoxy]-2-methoxybenzyl}-6-methylpyrimidin-4-ylamino)hexan-1-ol 
• 1376514-46-3 3-{4-[(2-amino-4-{[(3S)-1-(benzyloxy)hexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxyphenoxy}propan-1-ol 
• 1376514-47-4 3-{4-[(2-amino-4-{[(3S)-1-(benzyloxy)hexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxyphenoxy}propyl methanesulfonate 
• 1378275-59-2 (S)-2-{3-[4-({2-amino-4-[1-(benzyloxy)hexan-3-ylamino]-6-methylpyrimidin-5-yl}methyl)-3-methoxyphenoxy]propylamino}ethanol 
• 1378275-60-5 C₃₀H₄₃N₅O₃ 
• 1378275-63-8 (S)-N₄-[1-(benzyloxy)hexan-3-yl]-5-{2-methoxy-4-[3-(piperazin-1-yl)propoxy]benzyl}-6-methylpyrimidine-2,4-diamine 
• 1376514-48-5 N₄-[(3S)-1-(benzyloxy)hexan-3-yl]-5-{4-[3-(dimethylamino)propoxy]-2-methoxybenzyl}-6-methylpyrimidine-2,4-diamine 
• 1376514-10-1 2-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-5-[3-(dimethylamino)propoxy]phenol 

Relevant academic research and scientific papers

AMINOALKOXYPHENYL COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE

The invention concerns compounds of Formula (I): (I) wherein n, m, p, R1 and R2 are as defined in the description. The present invention also relates to processes for the preparation of such compounds, novel intermediates useful in the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of disease, for example cancer.

PHENOL COMPOUNDS ALS TOLL -LIKE RECEPTOR 7 AGONISTS

The invention concerns compounds of Formula (I): wherein R1, R2, R3 and Q are as defined in the description. The present invention also relates to processes for the preparation of such compounds, novel intermediates useful