64197-80-4

Usage

Uses

Used in Pharmaceutical Synthesis:
(S)-3-aminohexan-1-ol is used as a chiral building block for the development of pharmaceuticals and organic compounds. Its unique structure allows for the creation of enantiomerically pure substances, which is crucial for ensuring the desired biological activity and minimizing potential side effects.
Used in Therapeutic Applications:
In the field of medicine, (S)-3-aminohexan-1-ol is used as a potential therapeutic agent for metabolic disorders and neurodegenerative diseases. Its specific properties and interactions with biological systems make it a promising candidate for the treatment of these conditions.
Used in Chemical Research:
(S)-3-aminohexan-1-ol serves as an important compound in chemical research, particularly in the study of chirality and its effects on chemical reactions and biological activity. This knowledge can be applied to improve the design and synthesis of new drugs and materials.

Upstream product

• 59663-70-6 ethyl 3-aminocaproate 
• 85144-28-1 tert-butyl hex-2-enoate 
• 22937-03-7 4-propylazetidin-2-one 

Relevant academic research and scientific papers

Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus

Toll-like receptor (TLR) 7 and 8 agonists can potentially be used in the treatment of viral infections and are particularly promising for chronic hepatitis B virus (HBV) infection. An internal screening effort identified a pyrimidine Toll-like receptor 7 and 8 dual agonist. This provided a novel alternative over the previously reported adenine and pteridone type of agonists. Structure-activity relationship, lead optimization, in silico docking, pharmacokinetics, and demonstration of ex vivo and in vivo cytokine production of the lead compound are presented.

A novel approach to homochiral β-amino acids 1

An efficient synthesis of γ-aryl or alkyl substituted β-amino acids starting from N-Cbz-L-homoserine lactone via the formation of α-amino aryl, alkenyl or alkynyl ketones with the original α-carbon chirality retained as such is described. Copyright

Preparation of esters of phosphorus acids

Esters of phosphorus acids are prepared by an improved process whereby aromatic alcohols and phosphorus halides are reacted at specified temperatures in the presence of amine catalysts thereby providing high yields of substantially pure esters and allowing preparation of selected halogen-containing mono- and di-esters of phosphorus acids wherein halogen is directly bonded to phosphorus having substantially no side reactant contamination. The phosphorus esters are useful as intermediates in the preparation of plasticizers, oil additives and functional fluids.