1376622-86-4 Usage
General Description
(R,R,R,R)-N(1)-benzyl-2-(4'-methoxyphenyl)-3-acetoxy-4-benzyloxy-5-methylpyrrolidine is a complex chemical compound with multiple functional groups. It contains a benzyl group, a methoxyphenyl group, an acetoxy group, a benzyloxy group, and a methyl group attached to a pyrrolidine ring. The presence of these functional groups suggests that the compound may have pharmaceutical applications, as benzyl and methyl groups are commonly found in pharmaceutical compounds. The acetoxy and benzyloxy groups suggest that the compound may have potential use as a prodrug, where the compound is metabolized in the body to release an active pharmaceutical ingredient. The complexity of (R,R,R,R)-N(1)-benzyl-2-(4'-methoxyphenyl)-3-acetoxy-4-benzyloxy-5-methylpyrrolidine indicates that it may have a range of potential biological activities, and further research is needed to fully understand its properties and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1376622-86-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,6,6,2 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1376622-86:
(9*1)+(8*3)+(7*7)+(6*6)+(5*6)+(4*2)+(3*2)+(2*8)+(1*6)=184
184 % 10 = 4
So 1376622-86-4 is a valid CAS Registry Number.
1376622-86-4Relevant academic research and scientific papers
Ring-closing iodoamination of homoallylic amines for the synthesis of polysubstituted pyrrolidines: Application to the asymmetric synthesis of (-)-codonopsinine
Davies, Stephen G.,Lee, James A.,Roberts, Paul M.,Thomson, James E.,West, Callum J.
, p. 4302 - 4319 (2012/07/16)
Ring-closing iodoamination of (E)-configured, N-α-methyl-p- methoxybenzyl protected homoallylic amines upon treatment with I2 and NaHCO3 in MeCN occurs with concomitant loss of the N-α-methyl-p-methoxybenzyl group to give 3-iodopyrrolidines in >99:1 dr. This transformation was used as one of the key steps in the total asymmetric synthesis of (-)-codonopsinine, which was achieved in seven steps (from commercially available tert-butyl crotonate) in 5% overall yield and >99:1 dr.
