1376678-62-4

Basic information

• Product Name: C₂₄H₂₈O₂S₄
• Synonyms: C₂₄H₂₈O₂S₄
• CAS NO: 1376678-62-4
• Molecular Weight: 476.749
• Mol File: 1376678-62-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₈O₂S₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₈O₂S₄(1376678-62-4)
• EPA Substance Registry System: C₂₄H₂₈O₂S₄(1376678-62-4)

Safety Data

• Hazardous Substances Data: 1376678-62-4(Hazardous Substances Data)

Upstream product

• 41047-90-9 1,3-Bis(1,3-dithian-2-yl)benzol 
• 25109-86-8 methyl 2-(2-bromoethyl)benzoate 
• 626-19-7 Isophthalaldehyde 

Downstream Products

• 949155-92-4 methyl 2-(3-(3-formylphenyl)-3-oxopropyl)benzoate 

Relevant articles and documents

Practical synthesis of methyl (E)-2-(3-(3-(2-(7-chloro-2-quinolinyl) ethenyl)phenyl)-3-oxopropyl)benzoate, a key intermediate of Montelukast

A novel and practical synthetic route is presented for the preparation of methyl-(E)-2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl) benzoate, the key intermediate of Montelukast, a leukotriene antagonist. The main diarylpropane framework was prepared via a polarity conversation reaction resulting in an acyl anion equivalent followed by a nucleophilic substitution reaction. The overall yield of this approach was 61%. This method is simple for operation and suitable for industrial production.