137693-54-0Relevant academic research and scientific papers
Scandium trifluoromethanesulfonate as an extremely active Lewis acid catalyst in acylation of alcohols with acid anhydrides and mixed anhydrides
Ishihara, Kazuaki,Kubota, Manabu,Kurihara, Hideki,Yamamoto, Hisashi
, p. 4560 - 4567 (2007/10/03)
Scandium trifluoromethanesulfonate (triflate), which is commercially available, is a practical and useful Lewis acid catalyst for acylation of alcohols with acid anhydrides or the esterification of alcohols by carboxylic acids in the presence of p-nitrobenzoic anhydrides. The remarkably high catalytic activity of scandium triflate can be used for assisting the acylation by acid anhydrides of not only primary alcohols but also sterically-hindered secondary or tertiary alcohols. The method presented is especially effective for selective macrolactonization of ω-hydroxy carboxylic acids.
Improved preparation of angelate esters
Hartmann, Benoit,Kanazawa, Alice M.,Depres, Jean-Pierre,Greene, Andrew E.
, p. 5077 - 5080 (2007/10/02)
A new procedure has been developed for the efficient preparation of angelate esters from alcohols. The alcohol is treated in dry toluene at 70-80°C for 19-36 h with a mixed anhydride prepared from angelic acid and 2,4,6-trichlorobenzoyl chloride. In the absence of base, no tiglate ester is produced.
