137694-12-3

Upstream product

• 10133-06-9 methyl (+/-)-trans-(2,3)-epoxy butanoate 
• 100-51-6 benzyl alcohol 
• 38410-83-2 (2S,3R)-(-)-methyl 2,3-dihydroxybutanoate 
• 100-39-0 benzyl bromide 
• 620-05-3 iodomethylbenzene 

Downstream Products

• 129006-26-4 (2S,3S)-3-Benzyloxy-2-(3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxy)-butyric acid methyl ester 
• 129006-26-4 (2R,3R)-3-Benzyloxy-2-(3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxy)-butyric acid methyl ester 
• 129006-22-0 methyl 2-acetoxy-3-benzyloxybutyrate 
• 129099-54-3 methyl (2R,3R)-2-acetoxy-3-benzyloxybutyrate 
• 129099-51-0 Methyl (2S,3S)-3-benzyloxy-2-hydroxybutanoate 

Relevant academic research and scientific papers

Regioselective protection of threo-2,3-dihydroxybutanoic esters

Monoprotected derivatives of optically pure diolester 1 are regioselectively constructed by lipase-based methodologies as well as via the stannylene acetal of 1.

Selective monoalkylation of acyclic diols by means of dibutyltin oxide and fluoride salts

Fluoride anion was found to promote monoalkylation reaction of diols by the stannylene acetal method, and selective monoalkylation of various acyclic diols was accomplished in good yields under mild conditions by employing this new method. Functional groups such as carboxylic acid ester, carboxamide, carbamate, nitrile, alkyl chloride, and ether were not affected under the reaction conditions.