1377187-01-3Relevant academic research and scientific papers
HPLC-assisted automated oligosaccharide synthesis
Ganesh, N. Vijaya,Fujikawa, Kohki,Tan, Yih Horng,Stine, Keith J.,Demchenko, Alexei V.
supporting information; experimental part, p. 3036 - 3039 (2012/08/14)
A standard HPLC was adapted to polymer supported oligosaccharide synthesis. Solution-based reagents are delivered using a software-controlled solvent delivery system. The reaction progress and completion can be monitored in real time using a standard UV detector. All steps of oligosaccharide assembly including loading, glycosylation, deprotection, and cleavage can be performed using this setup.
