1377689-07-0Relevant articles and documents
Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors
Liu, Jia-Jia,Sun, Juan,Fang, Yun-Bin,Yang, Yong-An,Jiao, Rui-Hua,Zhu, Hai-Liang
, p. 998 - 1008 (2014/02/14)
A series of novel 4,5-dihydropyrazole derivatives (4a-4t), containing the dinitrobenzotrifluoride moiety, as DNA gyrase inhibitors were designed and synthesized. Based on the preliminary results, compounds 4d, 4h and 4t with potent inhibitory activity in
Design, synthesis and biological evaluation of novel chalcone derivatives as antitubulin agents
Zhang, Hui,Liu, Jia-Jia,Sun, Jian,Yang, Xian-Hui,Zhao, Ting-Ting,Lu, Xiang,Gong, Hai-Bin,Zhu, Hai-Liang
experimental part, p. 3212 - 3218 (2012/07/14)
A series of novel chalcone derivatives have been designed and synthesized, and their biological activities were also evaluated as potential inhibitors of tubulin. These compounds were assayed for growth-inhibitory activity against MCF-7 and A549 cell line