13780-71-7

Usage

Chemical Description

Boronic acid is an organic compound containing boron, carbon, and hydrogen atoms.

Upstream product

• 14333-13-2 permanganate(VII) ion 
• 14452-61-0 diborane 
• 80937-33-3 oxygen 
• 7732-18-5 water 

Downstream Products

• 169126-63-0 5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthylboronic Acid 
• 196960-96-0 3-(t-butyl)-4-methoxyphenyl boronic acid 
• 7424-72-8 9-(naphthyl-2-yl)anthracene 
• 1246382-96-6 4-{3-chloro-4-[3,3,3-trifluoro-2-hydroxy-2-(6-methoxy-pyridin-3-yl)-1-methyl-propyl]-phenoxy}-benzoic acid methyl ester 
• 920449-57-6 2-(2,4,6-trimethylphenyl)thiophene 
• 174265-12-4 2-bromo-5-chlorobenzaldehyde 
• 1299485-57-6 1-(4-n-Propylphenylethynyl)-4-[E-1,2-difluoro-2-(4-trifluoromethylphenyl)ethylenyl]naphthalene 
• 1232102-14-5 {6-[4'-(di-naphthalene-2-yl-amino)-biphenyl-4-yl]-pyrene-1-yl}naphthalene-2-yl-phenyl-amine 
• 1009303-54-1 {5-[2-Chloro-4-((R)-3-methyl-morpholin-4-yl)-pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-phenyl}-methanol 
• 943406-22-2 4-(3-(3,4-dimethylcyclopenta-1,3-dienone)-4-(cyclohexylamino)benzyl)-2-(3,4-dimethylcyclopenta-1,3-dienone)-N-cyclohexylbenzeneamine 
• 756839-27-7 [5-Fluoro-2-(1-cyclobutylmethyl-1H-indazol-5-ylamino)-benzyl]-carbamic acid tert-butyl ester 
• 291533-88-5 Methyl-[4'-phenyloxy-(1,1'-biphenyl)-4-yl]-sulfide 
• 108-95-2 phenol 
• 205818-25-3 1-(3-benzyloxyphenyl)-2-(4-methoxyphenyl)-6-methoxynaphthalene 

Relevant academic research and scientific papers

Microwave spectrum of borinic acid BH2OH

The microwave spectrum of BH2OH, a transient intermediate in the reaction between diborane and water, has been detected and analyzed.This molecule has also been found in the reaction between diborane and oxygen.The lifetime of BH2OH in a copper waveguide cell is a few seconds, which is much shorter than that of BH(OH)2.The rotational and centrifugal distortion constants have been getermined for the 11BH2OH, 10BH2OH, 11BD2OD11BH2 18OH species.From the rotational constants the molecular structure has been determined as r(B-O) = 1.352(4) Angstroem, r(O-H) = 0.967(14) Angstroem, BOH = 112.0(17)deg, HcBO = 121.8(8)deg, andHtBO = 117.2(8) deg, the r(B-H) = 1200 Angstroem being assumed.For the normal species, the dipole moments have been determined as μa = 0.497(7)D, μb = 1.423(15)D, and μtotal = 1.506 D.The quadrupole coupling constants have also been determined.

Oxidation-responsive poly(amino ester)s containing arylboronic ester and self-immolative motif: Synthesis and degradation study

We report the synthesis of a new type of amphiphilic poly(amino ester)s which can be completely degraded in aqueous media via H2O2 oxidation. The polymers were prepared by the controlled Michael-type addition polymerization of a phenylboronic pinacol ester-containing diacrylate and N-aminoethylpiperazine, followed by postmodification with mPEG5K-succinimide ester. Upon oxidation, the side chain phenylboronic esters will be transformed into phenol groups which can trigger the sequential self-immolative process to degrade the polymer main chain. Meanwhile, the amino groups on the polymer main chain are capable of trapping the highly active quinone methides generated in situ during the oxidative degradation of the polymers. Based on the detailed oxidation kinetics and products of several model compounds, the H 2O2-triggered degradation of nanoparticles of these copolymers was investigated by NMR spectroscopy, GPC, and Nile red fluorescence probe. The results demonstrate that the poly(amino ester) backbones were completely degraded by H2O2, resulting in the dissociation of nanoparticles. Oxidative degradation rates of the nanoparticles could be accelerated by increasing the concentration of H2O2, the PEGylation degree, or the pH of the buffer. Interestingly, the in situ formed quinone methides could be captured by secondary amines due to their higher nucleophilicity than H2O. Of potential importance, these amphiphilic oxidation-responsive copolymers are sensitive to stimulation of 200 μM H 2O2; therefore, they may find application in the field of intelligent drug/gene delivery systems.