1378029-94-7

Upstream product

• 501-65-5 diphenyl acetylene 
• 1446513-60-5 thiomorpholin-4-yl benzoate 
• 20259-38-5 cis-Stilbenyl-diisobutyl-aluminium 
• 123-90-0 Thiomorpholin 

Downstream Products

• 1259988-01-6 4-(1,2-diphenylethyl)thiomorpholine 

Relevant academic research and scientific papers

Cu-Catalyzed electrophilic amination of internal alkynes via hydroalumination

A straightforward and efficient method for the synthesis of 1,2-diaryl-substituted enamines through the Cu-catalyzed electrophilic amination reaction of O-benzoyl hydroxylamines with vinylaluminum reagents generated in situ from the Ni-catalyzed hydroalumination of readily accessible internal aryl acetylenes is described. The amination is catalyzed by 1 mol% CuCl without any additive at ambient temperature to afford new versatile enamines in good yield (61-91%) with high selectivity (>98% E-enamine).

NOVEL CATALYSTS

The present invention provides novel compounds and ligands that are useful in transition metal catalyzed cross-coupling reactions. For example, the compounds and ligands of the present invention are useful in palladium or gold catalyzed cross-coupling reactions.