1378039-81-6

Basic information

• Product Name: 3,5-dichloro-4-(7-fluoro-5-oxy-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile
• Synonyms: 3,5-dichloro-4-(7-fluoro-5-oxy-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile
• CAS NO: 1378039-81-6
• Molecular Weight: 323.113
• Mol File: 1378039-81-6.mol

Chemical Properties

• CAS DataBase Reference: 3,5-dichloro-4-(7-fluoro-5-oxy-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dichloro-4-(7-fluoro-5-oxy-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile(1378039-81-6)
• EPA Substance Registry System: 3,5-dichloro-4-(7-fluoro-5-oxy-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile(1378039-81-6)

Safety Data

• Hazardous Substances Data: 1378039-81-6(Hazardous Substances Data)

Upstream product

• 1378039-80-5 3,5-dichloro-4-(7-fluoro-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile 
• 1378039-79-2 4-{[1-(4-azido-5-fluoro-pyridin-3-yl)-meth-(E)-ylidene]-amino}-3,5-dichloro-benzonitrile 
• 2546-56-7 4-chloro-3-fluoro-pyridine 

Downstream Products

• 1378039-82-7 3,5-dichloro-4-(4-chloro-7-fluoro-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile 
• 1378039-83-8 3,5-dichloro-4-(4-bromo-7-fluoro-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile 
• 1378039-84-9 [2-(2,6-dichloro-4-cyanophenyl)-7-fluoro-2H-pyrazolo[4,3-c]pyridin-4-yl]-carbamic acid tert-butyl ester 
• 1378039-85-0 4-(4-amino-7-fluoropyrazolo[4,3-c]pyridin-2-yl)-3,5-dichlorobenzonitrile 
• 1378037-90-1 4-[7-bromo-4-(6-methyl-pyrimidin-4-ylamino)-pyrazolo[4,3-c]pyridin-2-yl]-3,5-dichlorobenzonitrile 
• 1378039-97-4 3,5-dichloro-4-(4,7-dibromo-pyrazolo[4,3-c]pyridin-2-yl)-benzonitrile 

Relevant articles and documents

PYRAZOLOPYRIDINES AND PYRAZOLOPYRIDINES AND THEIR USE AS TYK2 INHIBITORS

The invention provides compounds of Formula (I), stereoisomers or pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula (I) and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of using the compound or composition in therapy, as TYK2 Kinase inhibitors.