137807-24-0Relevant academic research and scientific papers
Action of (2-Benzothiazolyl)methyllithium with Organic Polar Functions
Costa, Maria Virginia,Brembilla, Alain,Roizard, Denis,Lochon, Pierre
, p. 1933 - 1936 (2007/10/02)
(2-Benzothiazolyl)methyllithium reacts quickly at low temperature (-78 deg C) with a variety of organic electrophiles like aldehydes, ketones, carboxylic esters, nitriles and acyl chlorides.Such reactions lead to an easy introduction of alcohol, keto-enol or amine-enamine functional groups in extracyclic position with a stereoselective preference.These polyfunctional compounds whose synthesis is difficult by other pathways, are interesting, in particular, because of their ability to form intramolecular hydrogen bounds.
