13781-27-6

Basic information

• Product Name: (5-IODO-THIOPHEN-2-YL)-METHANOL
• Synonyms: (5-IODO-THIOPHEN-2-YL)-METHANOL
• CAS NO: 13781-27-6
• Molecular Formula: C₅H₅IOS
• Molecular Weight: 240.06207
• Mol File: 13781-27-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 291.8°C at 760 mmHg
• Flash Point: 130.3°C
• Appearance: /
• Density: 2.091g/cm³
• Vapor Pressure: 0.000873mmHg at 25°C
• Refractive Index: 1.692
• PKA: 13.53±0.10(Predicted)
• CAS DataBase Reference: (5-IODO-THIOPHEN-2-YL)-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (5-IODO-THIOPHEN-2-YL)-METHANOL(13781-27-6)
• EPA Substance Registry System: (5-IODO-THIOPHEN-2-YL)-METHANOL(13781-27-6)

Safety Data

• Hazardous Substances Data: 13781-27-6(Hazardous Substances Data)

Usage

General Description

(5-IODO-THIOPHEN-2-YL)-METHANOL, also known as 5-iodothiophene-2-yl methanol, is a chemical compound with the molecular formula C6H5IO. It is a derivative of thiophene, a five-membered aromatic ring containing sulfur. The presence of an iodine atom in the molecule makes it a halogenated compound. This chemical is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its unique structure and functional groups make it a valuable reagent in organic chemistry research and industry. Additionally, it may have potential applications in the field of materials science and as a starting material for the preparation of various functionalized thiophenes.

InChI:InChI=1/C5H5IOS/c6-5-2-1-4(3-7)8-5/h1-2,7H,3H2

Upstream product

• 636-72-6 2-thiophenemethanol 
• 98-03-3 thiophene-2-carbaldehyde 

Downstream Products

• 875584-27-3 C₅₂H₅₀IN₅O₁₁S 
• 32358-94-4 5-methyl-2,2'-bithiophene-5'-carboxaldehyde 

Relevant articles and documents

Luminescent molecular solar concentrators made of multi-Bodipy dyes

The synthesis of photoactive arrays consisting of Bodipy scaffoldings is described. The synthetic strategy involved first the construction of functionalised modules, then the use of specific Knoevenagel reactions. Boron-protection is required to avoid self-condensation. Comparison of thienylBodipy dyes with their phenyl analogues showed them to be both less chemically stable and more weakly fluorescent. In the multichromophoric species, efficient cascade energy transfer occurs upon absorption in the highest energy unit. The redox activity of the mixed dyes is analysed in terms of the behaviour of specific reference compounds.

Clean and Efficient Iodination of Thiophene Derivatives

Iodination of thiophene derivatives is realized using a simple, fast, and efficient methodology. Iodination of thiophene and 2- or 3-substituted or 3,4-disubstituted thiophenes with N-iodosuccinimide (NIS) activated with 4-toluenesulfonic acid in ethanol gives pure iodinated products that require no further purification.