13781-66-3 Usage
General Description
2-(Thiophen-3-yl)acetaMide is a chemical compound with the molecular formula C8H9NOS. It is an amide derivative of thiophene, containing a thiophene ring with an acetamide group attached to the 2-position. 2-(Thiophen-3-yl)acetaMide is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various bioactive molecules and pharmaceutical drugs. It has potential applications in the development of new drugs for the treatment of various diseases and disorders. Additionally, its unique structural properties make it an interesting target for further study in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 13781-66-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,8 and 1 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 13781-66:
(7*1)+(6*3)+(5*7)+(4*8)+(3*1)+(2*6)+(1*6)=113
113 % 10 = 3
So 13781-66-3 is a valid CAS Registry Number.
13781-66-3Relevant articles and documents
Nitrile Hydration Reaction Using Copper Iodide/Cesium Carbonate/DBU in Nitromethane-Water
Kuwabara, Jun,Sawada, Yoshiharu,Yoshimatsu, Mitsuhiro
supporting information, p. 2061 - 2065 (2018/09/14)
The catalytic nitrile hydration (amide formation) in a copper iodide/cesium carbonate/1,8-diazabicyclo[5.4.0]undec-7-ene/nitromethane-water system is described. The protocol is robust and reliable; it can be applied to a broad range of substrates with high chemoselectivity.
Direct catalytic formation of primary and tertiary amides from non-activated carboxylic acids, employing carbamates as amine source
Tinnis, Fredrik,Lundberg, Helena,Adolfsson, Hans
supporting information, p. 2531 - 2536 (2012/11/06)
The operationally simple titanium(IV)- or zirconium(IV)-catalyzed direct amidation of non-activated carboxylic acids with ammonium carbamates generates primary, and tertiary N,N-dimethyl-substituted amides in good to excellent yields. Copyright
