1378233-83-0

Basic information

• Product Name: (E)-3-(nitroxy)propyl 3-(3-methoxy-4-(3-(nitroxy)propoxy)phenyl)acrylate
• CAS NO: 1378233-83-0
• Molecular Weight: 400.342
• Mol File: 1378233-83-0.mol

Chemical Properties

• CAS DataBase Reference: (E)-3-(nitroxy)propyl 3-(3-methoxy-4-(3-(nitroxy)propoxy)phenyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(nitroxy)propyl 3-(3-methoxy-4-(3-(nitroxy)propoxy)phenyl)acrylate(1378233-83-0)
• EPA Substance Registry System: (E)-3-(nitroxy)propyl 3-(3-methoxy-4-(3-(nitroxy)propoxy)phenyl)acrylate(1378233-83-0)

Safety Data

• Hazardous Substances Data: 1378233-83-0(Hazardous Substances Data)

Upstream product

• 1378942-63-2 (E)-3-bromopropyl 3-(4-(3-bromopropoxy)-3-methoxyphenyl)acrylate 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 

Relevant articles and documents

Design and synthesis of novel NO-donor-ferulic acid hybrids as potential antiatherosclerotic drug candidates a

Novel NO-donor-ferulic acid hybrids were designed and synthesized through a symbiotic approach using ferulic acid and three different NO-donating groups, such as nitric ester, 4-hydroxyl-3-phenylfuroxan, and 4-hydroxymethyl-3- phenylsulfonylfuroxan. Antioxidant, nitric oxide release, and vasodilator properties studies showed that the target phenylsulfonylfuroxan 14, especially 14c, while keeping the antioxidant activity, showed more NO release activity and vasodilating activity than isosorbide dinitrate (ISDN). Thus, 14c may be considered a novel potent anti-atherosclerosis drug candidate.