1378239-22-5Relevant academic research and scientific papers
Preparation of modified peptides: Direct conversion of α-amino acids into β-amino aldehydes
Saavedra, Carlos J.,Boto, Alicia,Hernandez, Rosendo
, p. 4448 - 4461 (2012)
A direct method for the transformation of α-amino acids into β-amino aldehydes was developed, and applied to the modification of the C-terminal residue of peptides. The method takes place in good yields and under mild conditions. The application of this methodology to the preparation of small peptides with γ-amino alcohol units, which are precursors of analogues of peptaibol antibiotics, is also described.
