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6-Fluoro-1H-pyrazolo[4,3-b]pyridine is a chemical compound belonging to the pyrazolopyridine class, characterized by the presence of a fluorine atom at the 6th position and a pyridine ring fused to a pyrazole ring. 6-fluoro-1H-pyrazolo [4,3-b]pyridine exhibits unique structural and electronic properties that make it a promising candidate for various applications in the pharmaceutical and chemical industries.

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  • 1378592-49-4 Structure
  • Basic information

    1. Product Name: 6-fluoro-1H-pyrazolo [4,3-b]pyridine
    2. Synonyms:
    3. CAS NO:1378592-49-4
    4. Molecular Formula:
    5. Molecular Weight: 137.116
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1378592-49-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-fluoro-1H-pyrazolo [4,3-b]pyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-fluoro-1H-pyrazolo [4,3-b]pyridine(1378592-49-4)
    11. EPA Substance Registry System: 6-fluoro-1H-pyrazolo [4,3-b]pyridine(1378592-49-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1378592-49-4(Hazardous Substances Data)

1378592-49-4 Usage

Uses

Used in Pharmaceutical Industry:
6-Fluoro-1H-pyrazolo[4,3-b]pyridine is used as an active pharmaceutical ingredient (API) for the treatment and/or prevention of influenza. Its unique chemical structure allows it to target specific viral proteins, inhibiting their function and thereby reducing the severity and duration of the flu.
The compound's antiviral properties make it a valuable addition to the arsenal of drugs used to combat influenza, which can be particularly beneficial in cases where resistance to existing antiviral medications has developed. Furthermore, its development and optimization could lead to the creation of new, more effective treatments for a range of viral infections.
In addition to its direct application as an antiviral agent, 6-fluoro-1H-pyrazolo[4,3-b]pyridine may also be used as a building block or intermediate in the synthesis of other pharmaceutical compounds with potential applications in various therapeutic areas. Its unique structural features and electronic properties make it an attractive candidate for further research and development in the field of medicinal chemistry.
Used in Chemical Research:
6-Fluoro-1H-pyrazolo[4,3-b]pyridine can also be utilized as a research tool in the field of chemical synthesis and materials science. Its unique structure and properties make it a valuable starting material for the development of new compounds with tailored properties for specific applications.
For example, the compound's fluorine atom can be used to introduce fluorination into other molecules, which can significantly alter their reactivity, stability, and biological activity. This makes 6-fluoro-1H-pyrazolo[4,3-b]pyridine a potentially useful building block for the synthesis of novel fluorinated compounds with applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Furthermore, the compound's structural features may also make it a valuable model system for studying the effects of fluorination on the properties and reactivity of pyrazolopyridine derivatives, providing valuable insights into the design and synthesis of new compounds with improved performance and functionality.

Check Digit Verification of cas no

The CAS Registry Mumber 1378592-49-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,8,5,9 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1378592-49:
(9*1)+(8*3)+(7*7)+(6*8)+(5*5)+(4*9)+(3*2)+(2*4)+(1*9)=214
214 % 10 = 4
So 1378592-49-4 is a valid CAS Registry Number.

1378592-49-4Downstream Products

1378592-49-4Relevant articles and documents

PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA

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Page/Page column 61; 62, (2017/09/02)

Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer,or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.

PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF

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Page/Page column 173, (2017/12/28)

Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.

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