137862-08-9Relevant academic research and scientific papers
Synthesis of alkene dipeptide isosteres employing the Wittig-Still rearrangement
Bol,Liskamp
, p. 5401 - 5404 (1991)
A new approach to the synthesis of alkene dipeptide isosteres is reported which features the use of the [2,3]-Wittig-Still rearrangement, carried out in hexane. As an example the synthesis of the alkene dipeptide isostere of Gly-Ala as part of the tripeptide isostere Z-Phe-GlyΨ[E-CH=CH]-(R,S)A1a-OH is described.
Synthesis of alkene dipeptide isosteres employing the Wittig-Still rearrangement
Bol,Liskamp
, p. 6425 - 6438 (2007/10/02)
A new approach to the synthesis of alkene dipeptide isosteres is reported which features the use of the [2,3]-Wittig-Still rearrangement, carried out in hexanes. Employing this rearrangement alkene dipeptide isosteres of 'Gly-Xxx' are accessible starting
