1378674-68-0

Basic information

• Product Name: 1-chloromethyl-2,4-difluoro-5-methyl-benzene
• Synonyms: 1-chloromethyl-2,4-difluoro-5-methyl-benzene
• CAS NO: 1378674-68-0
• Molecular Weight: 176.593
• Mol File: 1378674-68-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-chloromethyl-2,4-difluoro-5-methyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloromethyl-2,4-difluoro-5-methyl-benzene(1378674-68-0)
• EPA Substance Registry System: 1-chloromethyl-2,4-difluoro-5-methyl-benzene(1378674-68-0)

Safety Data

• Hazardous Substances Data: 1378674-68-0(Hazardous Substances Data)

Upstream product

• 315204-46-7 (2,4-difluoro-5-methyl-phenyl)-methanol 
• 1162674-66-9 2,4-difluoro-5-methyl-benzoic acid methyl ester 
• 367954-99-2 2,4-Difluoro-5-methylbenzoic acid 

Downstream Products

• 1442451-91-3 5-chloro-6-((2,4-difluoro-5-methylbenzyl)oxy)-3-(5-(2-(2-hydroxypropan-2-yl)pyrimidin-4-yl)-2-methylphenyl)-2-methylpyrimidin-4(3H)-one 

Relevant articles and documents

SUBSTITUTED PYRIMIDINONE-PHENYL-PYRIMIDINYL COMPOUNDS

The present disclosure provides pyrimidinone-phenyl-pyrimidinyl compounds useful in the treatment of p38 kinase mediated diseases, such as lymphoma and inflammatory disease, having the structure of Formula (I): wherein R1, R2, R3, R4 and R5 are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating p38 kinase mediated diseases using the compound.