1378993-22-6

Basic information

• Product Name: (4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone
• Synonyms: (4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone
• CAS NO: 1378993-22-6
• Molecular Weight: 253.732
• Mol File: 1378993-22-6.mol

Chemical Properties

• CAS DataBase Reference: (4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone(1378993-22-6)
• EPA Substance Registry System: (4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone(1378993-22-6)

Safety Data

• Hazardous Substances Data: 1378993-22-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
(4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone is used as a building block for the development of new pharmaceutical compounds due to its unique structure and potential pharmacological properties. Its ability to be integrated into various drug molecules makes it a valuable asset in the field of medicinal chemistry.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone is used as a research compound to explore its potential interactions with biological targets. This can lead to the discovery of new drugs or therapeutic agents that may have beneficial effects on human health.
Used in Drug Design and Synthesis:
(4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone is utilized as a key component in the design and synthesis of innovative drugs. Its structural features allow for the creation of diverse drug candidates that can be tailored to target specific medical conditions or diseases.
Used in Chemical Synthesis Industry:
Within the chemical synthesis industry, (4-amino-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone is used as an intermediate in the production of various chemical products, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its versatility in chemical reactions makes it a valuable compound for synthesizing a wide range of products.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 39608-47-4 3-chloro-4-nitrobenzoic acid 

Relevant articles and documents

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The present invention relates to the use of certain pyrrolopyridineamino derivatives (hereinafter referred to as “PPA derivatives”), particularly 1H-pyrrolo[3,2-c]pyridine-6-amino derivatives, to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps kinase itself. In particular, the present invention relates to PPA derivatives for use as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of the PPA derivatives, and pharmaceutical compositions comprising them. Formula (I)

PYRROLOPYRIDINEAMINO DERIVATIVES AS MPS1 INHIBITORS

The present invention relates to the use of certain pyrrolopyridineamino derivatives (hereinafter referred to as "PPA derivatives"), particularly 1H-pyrrolo[3,2-c]pyridine-6- amino derivatives, to inhibit the spindle checkpoint function of Monospindle 1 (Mps1 – also known as TTK) kinases either directly or indirectly via interaction with the Mps kinase itself. In particular, the present invention relates to PPA derivatives for use as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of the PPA derivatives, and pharmaceutical compositions comprising them. Formula (I)