137909-93-4

Upstream product

• 137909-97-8 (S)-3-((R)-Hydroxy-phenyl-methyl)-tetrahydro-thiopyran-4-one 
• 100-52-7 benzaldehyde 
• 1072-72-6 Tetrahydrothiopyran-4-one 
• 96-22-0 pentan-3-one 
• 64340-78-9 ((E)-1-Ethyl-propenyloxy)-dimethyl-silane 
• 137909-92-3 (3R,4S)-3-((R)-Hydroxy-phenyl-methyl)-tetrahydro-thiopyran-4-ol 
• 615-30-5 3-hydroxyl-2-methylpentanal 
• 16002-63-4 phenylmagnesium iodide 

Relevant academic research and scientific papers

The first example of a catalytic asymmetric aldol-Tishchenko reaction of aldehydes and aliphatic ketones

A number of combinations of Lewis acids and chiral ligands has been screened for the enantioselective direct tandem aldol condensation - Evans-Tishchenko reduction of aldehydes and ketones. Chiral ytterbium complexes were found to catalyze the condensatio

Titanium-mediated aldol-Tishchenko reaction: A stereoselective synthesis of differentiated anti 1,3-diol monoesters

anti 1,3-Diol monoesters were obtained in a high level of stereoselectivity by a one-pot aldol-Tishchenko reaction of ketones with aldehydes using substoichiometric amounts of titanium ate complexes.

Tandem aldol-reduction reaction of dimethylsilyl enolates: A new method for stereoselective preparation of 1,3-diols

In the presence of a catalytic amount of TBAF (Bu4NF), dimethylsilyl enolates derived from acyclic ketones reacted with aldehydes to give syn,syn-1,3-diols 7a and 8a with moderate to high diastereoselectivity. The stereochemical outcome can be attributed to a syn-selective aldol reaction and the subsequent 1,2-syn-selective intramolecular reduction.

Highly diastereoselective aldol reactions of 4-thianone: A new strategy for synthesis of polypropionate frames

The aldol reactions of the lithium enolate of 4-thianone with aldehydes yield the threo-isomers of aldols in a highly stereoselective manner and also showed high diastereoface selectivity. Other metal enolates of this reagent exhibited different behabiors