137933-00-7

Upstream product

• 137955-34-1 ethyl 3-hydroxy-3,3-di-(p-tolyl)propanoate 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 
• 71-43-2 benzene 
• 611-97-2 bis(p-methylphenyl)-methanone 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 2919-20-2 1,1-di(p-tolyl)ethylene 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 137933-01-8 3,3-bis(4-methylphenyl)prop-2-en-1-ol 
• 303110-67-0 (2S)-3-[4-(3,3-Di-p-tolyl-allyloxy)-phenyl]-2-ethoxy-propionic acid ethyl ester 
• 137932-82-2 3,3-di(4-methylphenyl)allyl acetate 
• 1338380-92-9 4,4'-(3-(2-iodophenoxy)prop-1-ene-1,1-diyl)bis(methylbenzene) 
• 1338381-07-9 3-(di-p-tolylmethyl)benzofuran 
• 93318-96-8 3,3-di-p-tolylacrylic acid 
• 1437756-71-2 7-methyl-4-(p-tolyl)-2H-chromen-2-one 

Relevant academic research and scientific papers

Photoinduced Oxidative Alkoxycarbonylation of Alkenes with Alkyl Formates

A photoinduced oxidative alkoxycarbonylation of alkenes initiated by intermolecular addition of alkoxycarbonyl radicals has been demonstrated. Employing alkyl formates as alkoxycarbonyl radical sources, a range of α,β-unsaturated esters were obtained with good regioselectivity and E selectivity under ambient conditions.

Scalable Electrochemical Dehydrogenative Lactonization of C(sp2/sp3)-H Bonds

A practical, electrochemical method is developed for the direct dehydrogenative lactonization of C(sp2/sp3)-H bonds under external oxidant- and metal-free conditions, delivering diverse lactones, including coumarin derivatives with excellent regioselectivity. The scalable nature of this newly developed electrochemical process was demonstrated on a 40 g scale following an operationally simple protocol. The remote lactonization of C(sp3)-H bonds would constitute an important synthetic advance toward electrochemical C-O bond formation.

Synthesis of coumarins via PIDA/I2-mediated oxidative cyclization of substituted phenylacrylic acids

A variety of functionalized coumarins were synthesized from substituted phenylacrylic acids via PIDA/I2-mediated and irradiation-promoted oxidative carbon-oxygen bond formation. Our studies show that the oxygen in the pendant carboxylic acid group cyclizes favorably to the aryl ring that is cis to it. The main advantages of this method include good functional group tolerance and the transition-metal-free characteristic. The Royal Society of Chemistry 2013.

Potassium tert-butoxide mediated Heck-type cyclization/isomerization- benzofurans from organocatalytic radical cross-coupling reactions

A transition metal-free Heck-type cyclization/isomerization reaction has been developed. Mediated by potassium tert-butoxide and phenanthroline a variety of benzofuran derivatives have been synthesized.

Design and synthesis of novel PPARα/γ/δ triple activators using a known PPARα/γ dual activator as structural template

Using a known dual PPARα/γ activator (5) as a structural template, SAR evaluations led to the identification of triple PPARα/γ/δ activators (18-20) with equal potency and efficacy on all three receptors. These compounds could become useful tools for studying the combined biological effects of PPARα/γ/δ activation.

Palladium catalyzed cyclocarbonylation of 3,3-diarylallyl acetates

Palladium-catalyzed cyclocarbonylation of 3,3-diarylallyl acetates afforded 4-aryl-substituted 1-naphthyl acetates where the cyclization occurred selectively on the more electron-rich ring.