1379456-55-9

Basic information

• Product Name: Br^(1-)*C₂₂H₃₁N₄O₄⁽¹⁺⁾
• CAS NO: 1379456-55-9
• Molecular Weight: 495.417
• Mol File: 1379456-55-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Br^(1-)*C₂₂H₃₁N₄O₄⁽¹⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: Br^(1-)*C₂₂H₃₁N₄O₄⁽¹⁺⁾(1379456-55-9)
• EPA Substance Registry System: Br^(1-)*C₂₂H₃₁N₄O₄⁽¹⁺⁾(1379456-55-9)

Safety Data

• Hazardous Substances Data: 1379456-55-9(Hazardous Substances Data)

Upstream product

• 616-47-7 1-methyl-1H-imidazole 
• 1371571-05-9 BrCH₂CO-Phe-Leu-OMe 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 64152-76-7 methyl (S)-2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-4-methylpentanoate 
• 38155-45-2 methyl L-phenylalanyl-L-leucinate hydrochloride 
• 7517-19-3 methyl (L)-leucinate hydrochloride 

Relevant articles and documents

Antimicrobial toxicity studies of ionic liquids leading to a 'hit' MRSA selective antibacterial imidazolium salt

Imidazolium salts can be classed as surfactants, detergents, ionic liquids, reagents, catalysts or solvents. A study of the toxicity and ecotoxicity of these salts yields valuable information for their use as pharmaceuticals as well as impact on the environment. Our approach to screen a series of chiral imidazolium salts for toxicity to bacteria and fungi, including clinical pathogen strains, has led to the identification of a 'hit' MRSA selective antimicrobial compound. Preliminary structure-activity-relationship (SAR) information (required position of l-phenylalanine and l-valine group) is also elucidated within this first generation of compounds. Conversely, most of the imidazolium salts were nontoxic (IC95 > 2 mM) to the 12 fungi strains and 8 bacteria strains screened, and we propose that they are suitable candidates for 'green chemistry' applications. Ecotoxicity studies (Biodegradation ISO 14593 'CO2 Headspace Test') of two bromide ionic liquids containing l-phenylalanine residues indicate that these ionic liquids passed the test (>60% in 28 days) and classed as readily biodegradable.