13795-45-4Relevant academic research and scientific papers
Synthesis of 2-(4,6-Dimethoxy-1,3,5-triazin-2-yloxyimino) derivatives: Application in solution peptide synthesis
Al-Warhi, Tarfah I.,AL-Hazimi, Hassan M.A.,El-Faham, Ayman,Albericio, Fernando
experimental part, p. 9403 - 9417 (2011/03/22)
A new class of 1,3,5-triazinyloxyimino derivatives were prepared, characterized and tested for reactivity in solution peptide synthesis. The new triazinyloxyimino derivatives failed to activate the carboxyl group during formation of peptide bonds, but gav
Reaction of [(Cp2TiCH3)(THF)+] [BPh4-] with tripeptide derivatives: Formation of cationic (peptide)titanocene complexes
Harmsen, Dirk,Erker, Gerhard,Froehlich, Roland,Kehr, Gerald
, p. 3156 - 3171 (2007/10/03)
A series of Z- and Boc-protected tripeptide methyl esters [Z-/Boc-5 to -12(pept)] was prepared using the amino acids glycine, alanine and valine. In both the alanine and the valine series a single glycine unit was introduced and its position inside the tr
Use of polymer-bound 4-dialkylaminopyridines in peptide synthesis
Frontin, F. Cavelier,Guendouz, F.,Jacquier, R.,Verducci, J.
, p. 463 - 467 (2007/10/02)
This work describes the use of polymer-bound 4-dialkylaminopyridines as catalyst in peptide bond formation.In comparison with their soluble analogues, such as DMAP, these less basic compounds are less favorable to formation of oxazolone intermediate, and lead to peptide bond formation in good yields, and generally very low racemization. Key words: DMAP; polymer-bound dialkylaminopyridines; peptide synthesis; racemization.
