137957-41-6

Basic information

• Product Name: N-(tert-butyl)-N-(4-ethylbenzyl)amine
• Synonyms: N-(tert-butyl)-N-(4-ethylbenzyl)amine;AKOS BBV-007357;AKOS LT-918X3333;N-(4-ETHYLBENZYL)-2-METHYL-2-PROPANAMINE;UKRORGSYN-BB BBV-007357;N-(4-ethylbenzyl)-2-methyl-2-propanamine(SALTDATA: HCl);N-[(4-ethylphenyl)methyl]-2-methylpropan-2-amine
• CAS NO: 137957-41-6
• Molecular Formula: C₁₃H₂₁N
• Molecular Weight: 191.31
• Mol File: 137957-41-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 260.5°C at 760 mmHg
• Flash Point: 100.2°C
• Appearance: /
• Density: 0.896g/cm³
• Vapor Pressure: 0.0122mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: N-(tert-butyl)-N-(4-ethylbenzyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(tert-butyl)-N-(4-ethylbenzyl)amine(137957-41-6)
• EPA Substance Registry System: N-(tert-butyl)-N-(4-ethylbenzyl)amine(137957-41-6)

Safety Data

• Hazardous Substances Data: 137957-41-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H21N/c1-5-11-6-8-12(9-7-11)10-14-13(2,3)4/h6-9,14H,5,10H2,1-4H3

Upstream product

• 75-64-9 tert-butylamine 
• 4748-78-1 4-ethylbenzylaldehyde 

Downstream Products

• 85623-71-8 N-tert-butyl α-(4-ethylphenyl) nitrone 

Relevant articles and documents

Br?nsted Acid Catalyzed Dearomatization by Intramolecular Hydroalkoxylation/Claisen Rearrangement: Diastereo- and Enantioselective Synthesis of Spirolactams

Described herein is a novel Br?nsted acid catalyzed intramolecular hydroalkoxylation/Claisen rearrangement, allowing the practical and atom-economic synthesis of a range of valuable spirolactams from readily available ynamides in generally good to excellent yields with excellent diastereoselectivities and broad substrate scope. Importantly, an unexpected dearomatization of nonactivated arenes and heteroaromatic compounds is involved in this tandem sequence. Moreover, an asymmetric version of this tandem cyclization was also achieved by efficient kinetic resolution by chiral phosphoric acid catalysis. In addition, the [3,3]-rearrangement is shown to be kinetically preferred over the related [1,3]-rearrangement by theoretical calculations.