1379656-74-2Relevant academic research and scientific papers
Diastereo- and enantioselective iridium-catalyzed carbonyl propargylation from the alcohol or aldehyde oxidation level: 1,3-enynes as allenylmetal equivalents
Geary, Laina M.,Woo, Sang Kook,Leung, Joyce C.,Krische, Michael J.
, p. 2972 - 2976 (2012/04/18)
Axial to axial to point chirality transfer: Exposure of conjugated enynes to alcohols in the presence of an iridium catalyst modified by a segphos ligand results in the generation of aldehyde-allenyliridium pairs and formation of enantiomerically enriched products of carbonyl anti-(α-methyl) propargylation (see scheme). An identical set of products are obtained from aldehydes under related transfer hydrogenation conditions by employing formic acid as a reductant. Copyright
