137967-69-2Relevant academic research and scientific papers
Boron Trifluoride Assisted Perfluoroalkylation of Carbon-Nitrogen Double Bonds
Uno, Hidemitsu,Okada, Shin-ichiro,Ono, Tetsushi,Shiraishi, Yasukazu,Suzuki, Hitomi
, p. 1504 - 1513 (1992)
In the presence of BF3*OEt2, (perfluoroalkyl)lithiums generated in situ from the reaction of primary perfluoroalkyl iodides and MeLi-LiBr reacted with imines, azines, and nitrones to afford perfluoroalkylated nitrogen-containing compounds in moderate to good yields.This method was successfully applied to the preparation of a (perfluoroalkyl)glycine and optically active perfluoroalkylated amines.
