1379803-49-2Relevant academic research and scientific papers
Synthesis of phloroglucinol monoaryl ethers
Sherwood, Alexander M.,Pond, David M.,Trudell, Mark L.
experimental part, p. 1208 - 1212 (2012/05/20)
A variety of novel functionalized phloroglucinol monoaryl ethers have been synthesized using a two-step procedure. Target ethers were synthesized by coupling electron-deficient aryl fluorides with 3,5-dimethoxyphenol via nucleophilic aromatic substitution (SNAr) in N-methylpyrrolidone and cesium carbonate. Subsequent boron tribromide-mediated demethylation gave a series of phloroglucinol monoaryl ethers in good overall yields. Georg Thieme Verlag Stuttgart New York.
