133116-83-3 Usage
Uses
Different sources of media describe the Uses of 133116-83-3 differently. You can refer to the following data:
1. 2-Fluoro-6-(trifluoromethyl)benzonitrile acts as a reagent in the synthesis of Quinolinecarboxamides for the treatment of autoimmune disorders.
2. 2-Fluoro-6-(trifluoromethyl)benzonitrile may be used in chemical synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 133116-83-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,1,1 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 133116-83:
(8*1)+(7*3)+(6*3)+(5*1)+(4*1)+(3*6)+(2*8)+(1*3)=93
93 % 10 = 3
So 133116-83-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H3F4N/c9-7-3-1-2-6(5(7)4-13)8(10,11)12/h1-3H
133116-83-3Relevant articles and documents
Copper-catalyzed trifluoromethylation of aryl iodides with potassium (trifluoromethyl)trimethoxyborate
Knauber, Thomas,Arikan, Fatih,Roeschenthaler, Gerd-Volker,Goossen, Lukas J.
, p. 2689 - 2697 (2011)
Potassium (trifluoromethyl)trimethoxyborate is introduced as a new source of CF3 nucleophiles in copper-catalyzed trifluoromethylation reactions. The crystalline salt is stable on storage, easy to handle, and can be obtained in near-quantitative yields simply by mixing B(OMe)3, CF3SiMe3, and KF. The trifluoromethylation reagent allows the conversion of various aryl iodides into the corresponding benzotrifluorides in high yields under mild, base-free conditions in the presence of catalytic quantities of a CuI/1,10-phenanthroline complex.
