1379822-79-3Relevant academic research and scientific papers
Bicyclic oxygen heterocycles from γ,δ-unsaturated alcohols: Synthetic targets inspired by blepharocalyxin D
Bunt, Adam J.,Bailey, Christopher D.,Cons, Benjamin D.,Edwards, Sophie J.,Elsworth, Jon D.,Pheko, Tshepo,Willis, Christine L.
supporting information; experimental part, p. 3901 - 3904 (2012/06/04)
trans-2,8-Dioxabicyclodecanes were prepared in high yield with the creation of up to three stereocenters in a single pot by the acid-mediated reaction of γ,δ-unsaturated alcohols with aldehydes (see scheme, Bn=benzyl). This versatile reaction enables the stereoselective introduction of substituents at the C3, C4, C7, and C9 positions of the bicyclic framework. Copyright
