1380100-04-8

Basic information

• Product Name: (E)-1-(4-methoxybenzyl)-2-(3-nitrostyryl)piperidine
• CAS NO: 1380100-04-8
• Molecular Weight: 352.433
• Mol File: 1380100-04-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(4-methoxybenzyl)-2-(3-nitrostyryl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(4-methoxybenzyl)-2-(3-nitrostyryl)piperidine(1380100-04-8)
• EPA Substance Registry System: (E)-1-(4-methoxybenzyl)-2-(3-nitrostyryl)piperidine(1380100-04-8)

Safety Data

• Hazardous Substances Data: 1380100-04-8(Hazardous Substances Data)

Upstream product

• 928-90-5 5-hexyl-1-ol 
• 79496-61-0 hex-5-ynyl methanesulphonate 

Relevant articles and documents

Carbenylative amination with N-tosylhydrazones

A Pd-catalyzed reaction of vinyl iodides and N-tosylhydrazones that assembles η3-allyl ligands through carbene insertion is demonstrated. Intramolecular trapping with nitrogen nucleophiles generates good yields of cinnamyl and pentadienyl amines like those found in alkaloid natural products. Carbenylative amination was the key reaction to complete the synthesis of the alkaloid caulophyllumine B. Migratory insertion was biased to provide allylamines with optical purity up to 64% ee, but in a lower yield.