1380107-36-7

Basic information

• Product Name: 3-(benzylcarbamoyl)oxetan-3-yl acetate
• Synonyms: 3-(benzylcarbamoyl)oxetan-3-yl acetate
• CAS NO: 1380107-36-7
• Molecular Weight: 249.266
• Mol File: 1380107-36-7.mol

Chemical Properties

• CAS DataBase Reference: 3-(benzylcarbamoyl)oxetan-3-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(benzylcarbamoyl)oxetan-3-yl acetate(1380107-36-7)
• EPA Substance Registry System: 3-(benzylcarbamoyl)oxetan-3-yl acetate(1380107-36-7)

Safety Data

• Hazardous Substances Data: 1380107-36-7(Hazardous Substances Data)

Upstream product

• 6704-31-0 oxetan-3-one 
• 88333-03-3 Benzyl isocyanide 
• 64-19-7 acetic acid 

Relevant articles and documents

Passerini reactions for the efficient synthesis of 3,3-disubstituted oxetanes

Three-component reactions of oxetan-3-ones with isocyanides and carboxylic acids produce 3,3-disubstituted oxetanes in good yields. Good levels of diastereocontrol (dr = 4:1) can be achieved in these Passerini reactions when the oxetane nucleus possesses a bulky cyclohexyl substituent at C-2. The (2S,3R)-stereochemistry of the major diastereomer was confirmed by X-ray crystallography after ester hydrolysis, and a possible mechanism to account for the diastereofacial selectivity is presented.