1380158-99-5Relevant academic research and scientific papers
Highly regioselective synthesis of novel 4-O-phosphorylated paeonol analogs
Ju, Zhiyu,Li, Gongchun,Wang, Jie,Ye, Yong,Yang, Fengling,Zhao, Yufen
experimental part, p. 859 - 863 (2012/07/31)
4-O-phosphorylated paeonol derivatives were conveniently prepared by a facile method. Resacetophenone was prepared by the Friedel-Crafts acylation reaction of acetic acid with resorcinol. It was then phosphorylated regioselectively at the 4-O position using the Atherton-Todd reaction. An efficient, highly regioselective method to synthesize 4-O-phosphorylated paeonol derivatives is provided, and the approach has the merits of mild reaction conditions. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright Taylor and Francis Group, LLC 2012.
