1189-24-8Relevant articles and documents
Phosphine-catalyzed addition of P(O)-H compounds to ethyl phenylpropiolate
Salin, Alexey V.,Il'in, Anton V.,Shamsutdinova, Fanuza G.,Fatkhutdinov, Albert R.,Galkin, Vladimir I.,Islamov, Daut R.,Kataeva, Olga N.
, p. 6282 - 6286 (2015)
An efficient PBu3-catalyzed α-addition of the P(O)-H bond to ethyl phenylpropiolate has been developed. This strategy offers a facile method for the preparation of synthetically useful alkenyl phosphonates and phosphinates proceeding under neut
Continuous flow alcoholysis of dialkyl h-phosphonates with aliphatic alcohols
Bálint, Erika,Tajti, ádám,Tóth, Nóra,Keglevich, Gy rgy
, (2018)
The continuous flow alcoholysis of dialkyl H-phosphonates by aliphatic alcohols in the absence of a catalyst was elaborated using a microwave (MW) reactor equipped with a flow cell. By the precise control of the reaction conditions, the synthesis could be fine-tuned towards dialkyl H-phosphonates with two different and with two identical alkyl groups. In contrast to the “traditional” batch alcoholysis, flow approaches required shorter reaction times, and the products became available at a larger scale.
Synthesis of H-Phosphonate Intermediates and Their Use in Preparing the Herbicide Glyphosate
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Paragraph 0036; 0044; 0047, (2014/10/16)
The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride.
