1380292-92-1Relevant articles and documents
Purine compound containing bicyclic group, and preparation method thereof
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Paragraph 0123; 0137; 0138, (2019/10/01)
The invention provides a purine compound containing a bicyclic group which is shown as a formula (I) and a formula (II) and a pharmaceutically acceptable salt, and a preparation method thereof. The compound is an inhibitor of histone methyltransferase DOT1L, and can be used for treating diseases caused by the abnormity of enzyme activity, such as tumor.